Age-dependent hearing loss in normal hearing mice
نویسندگان
چکیده
منابع مشابه
With Normal Hearing and Cochlear Hearing Loss
Distortion product emissions (DPEs) at 2f1 f2 frequencies were measured in 53 human ears; 21 of them exhibited cochlear hearing loss. DPEs were obtained as a function of stimulus level (DPE growth curves) at seven frequency regions between 707 Hz and 5656 Hz. Several distinctly different shapes or patterns of DPE growth curves were observed. These included single-segment monotonic growth curves...
متن کاملGlycinergic synaptic transmission in the cochlear nucleus of mice with normal hearing and age-related hearing loss.
The principal inhibitory neurotransmitter in the mammalian cochlear nucleus (CN) is glycine. During age-related hearing loss (AHL), glycinergic inhibition becomes weaker in CN. However, it is unclear what aspects of glycinergic transmission are responsible for weaker inhibition with AHL. We examined glycinergic transmission onto bushy cells of the anteroventral CN in normal-hearing CBA/CaJ mice...
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Inner ear cells are sensitive to some metabolic and hormonal disorders, but the relation between chronic renal failure (CRF), regular dialysis treatment (RDT) and sensorineural hearing loss (SNHL) is still a debatable field. The object of this paper was to verify the presence of SNHL in patients submitted to hemodialysis with different duration due to CRF and in those submitted to conservat...
متن کاملTitle: Glycinergic Synaptic Transmission in the Cochlear Nucleus of Mice with Normal Hearing and Age- 1 Related Hearing Loss 2
24 The principal inhibitory neurotransmitter in the mammalian cochlear nucleus (CN) is glycine. During 25 age-related hearing loss (AHL), glycinergic inhibition becomes weaker in CN. However, it is unclear what 26 aspects of glycinergic transmission are responsible for weaker inhibition with AHL. We examined 27 glycinergic transmission onto bushy cells of the anteroventral CN in normal hearing ...
متن کاملAge-Related Hearing Loss in Mn-SOD Heterozygous Knockout Mice
Age-related hearing loss (AHL) reduces the quality of life for many elderly individuals. Manganese superoxide dismutase (Mn-SOD), one of the antioxidant enzymes acting within the mitochondria, plays a crucial role in scavenging reactive oxygen species (ROS). To determine whether reduction in Mn-SOD accelerates AHL, we evaluated auditory function in Mn-SOD heterozygous knockout (HET) mice and th...
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ژورنال
عنوان ژورنال: Die Naturwissenschaften
سال: 1974
ISSN: 0028-1042,1432-1904
DOI: 10.1007/bf00622976